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Determination of drug distributions in decomposed and buried postmortem tissues and bones of pigs administered of drugs    
Yazarlar (4)
İsmail Ethem Gören
Çukurova Üniversitesi, Türkiye
Nebile Dağlıoğlu
Çukurova Üniversitesi, Türkiye
Prof. Dr. Yusuf Kenan DAĞLIOĞLU Prof. Dr. Yusuf Kenan DAĞLIOĞLU
Çukurova Üniversitesi, Türkiye
Mete Korkut Gülmen
Çukurova Üniversitesi, Türkiye
Devamını Göster
Özet
Purpose Interpretation of drug levels in decomposed and buried corpses is difficult. We aimed to determine postmortem distribution of drugs in putrefied-decomposed visceral tissues and buried bones, and the effect of decomposition and burial on distribution of drugs in organs and bone tissues by administering drug groups selected from various drug classes to domestic pigs. Methods Pigs were divided into groups (n = 5) and dosed with a variety of drugs. Peripheral blood, organ and bone samples in different anatomical locations were collected from pigs killed. Organ samples were collected at postmortem 4th, 24th, 48th, 72nd and 96th hour. Then the corpses were buried below soil ground. Bone samples from buried corpses were collected at 5th and 10th months of the burial time by exhumation. All samples were analysed using liquid chromatography-tandem mass spectrometry after making sample …
Anahtar Kelimeler
Forensic toxicology | Drugs | Exhumation | Bone | Tissue | Pig
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Forensic Toxicology
Dergi ISSN 1860-8965 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SSCI
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 01-2019
Cilt No 38
Sayı 1
Sayfalar 129 / 140
Doi Numarası 10.1007/s11419-019-00497-8
Makale Linki http://link.springer.com/10.1007/s11419-019-00497-8