Determination of drug distributions in decomposed and buried postmortem tissues and bones of pigs administered of drugs
   
Yazarlar (4)
İsmail Ethem Gören Çukurova Üniversitesi, Türkiye
Nebile Dağlıoğlu Çukurova Üniversitesi, Türkiye
Prof. Dr. Yusuf Kenan DAĞLIOĞLU Çukurova Üniversitesi, Türkiye
Mete Korkut Gülmen Çukurova Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı FORENSIC TOXICOLOGY (Q2)
Dergi ISSN 1860-8965 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce Basım Tarihi 01-2020
Cilt / Sayı / Sayfa 38 / 1 / 129–140 DOI 10.1007/s11419-019-00497-8
Makale Linki http://link.springer.com/10.1007/s11419-019-00497-8
Özet
Purpose Interpretation of drug levels in decomposed and buried corpses is difficult. We aimed to determine postmortem distribution of drugs in putrefied-decomposed visceral tissues and buried bones, and the effect of decomposition and burial on distribution of drugs in organs and bone tissues by administering drug groups selected from various drug classes to domestic pigs. Methods Pigs were divided into groups (n = 5) and dosed with a variety of drugs. Peripheral blood, organ and bone samples in different anatomical locations were collected from pigs killed. Organ samples were collected at postmortem 4th, 24th, 48th, 72nd and 96th hour. Then the corpses were buried below soil ground. Bone samples from buried corpses were collected at 5th and 10th months of the burial time by exhumation. All samples were analysed using liquid chromatography-tandem mass spectrometry after making sample …
Anahtar Kelimeler
Forensic toxicology | Drugs | Exhumation | Bone | Tissue | Pig