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Woman with Sickle Cell Disease with Current Sigmoid Sinus Thrombosis and History of Inadequate Warfarin Use during a Past Thrombotic Event     
Yazarlar
Prof. Dr. Asuman ÇELİKBİLEK
Bozok Üniversitesi, Türkiye
Mehmet Çelikbilek
Bozok Üniversitesi, Türkiye
Alper Bozkurt
Turgut Özal Üniversitesi, Türkiye
Başak Karakurum Göksel
Başkent Üniversitesi, Türkiye
M Tan
H Ozdogu
Özet
We report a 20-year-old woman with sickle cell disease (SCD) who presented with a severe pulsating headache, nausea, and vomiting. Her history was significant for a past thrombotic event during which she had not used anticoagulation therapy as prescribed. Her mental status was mildly confused. On funduscopic examination, papilledema and retinal hemorrhages were found. Results of a computed tomogram were normal. A lumbar puncture demonstrated increased intracranial pressure (60 cm H2O). Magnetic resonance venography demonstrated a right sigmoid sinus thrombosis. Although SCD has been reported as a cause of thrombotic dural venous sinus events, this case increases the knowledge about neurological complications of SCD. The patient was treated with low molecular weight heparin, blood transfusions, acetazolamide, and methylprednisolone, and her symptoms and signs resolved.
Anahtar Kelimeler
Venous sinus thrombosis, Sickle cell disease, Inadequate warfarin use, Magnetic resonance venography
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCOPUS dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Case Reports in Neurology
Dergi ISSN 1662-680X
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce
Basım Tarihi 01-2009
Cilt No 1
Sayı 1
Sayfalar 15 / 19
Doi Numarası 10.1159/000216917
Makale Linki http://www.karger.com/doi/10.1159/000216917