Synthesis and characterization of a novel polyphosphazene and its application to biosensor in combination with a conducting polymer
Yazarlar (4)
Didem Ucan
Kırşehir Ahi Evran Üniversitesi, Türkiye
Fulya Ekiz Kanik
Middle East Technical University (Metu), Türkiye
Prof. Dr. Yunus KARATAŞ Kırşehir Ahi Evran Üniversitesi, Türkiye
Levent Toppare
Middle East Technical University (Metu), Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Sensors and Actuators B Chemical
Dergi ISSN 0925-4005 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce Basım Tarihi 10-2014
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 201 / 1 / 545–554 DOI 10.1016/j.snb.2014.05.040
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0925400514005693
Özet
An amperometric glucose biosensor was prepared successfully based on a conducting polymer, poly(4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine) (poly(SNS-NH2)) and a flexible hydrophilic polyphosphazene polymer, poly[(methoxyethoxy)ethoxy-co-3-formylphenoxy]phosphazene (PPA). Poly(SNS-NH2) was electrochemically polymerized on a graphite electrode to achieve a conducting immobilization matrix to improve the enzyme immobilization on the transducer surface. Moreover, to strengthen the immobilization, a polyphosphazene derivate bearing functional aldehyde group was designed, synthesized and used in the immobilization of glucose oxidase. Not only the amino groups in the structure of poly(SNS-NH2), but also the aldehyde groups in PPA were contributed to the covalent immobilization as well as the entrapping the biomolecules in PPA network during the immobilization process. This …
Anahtar Kelimeler
Conducting polymer | Covalent immobilization | Glucose biosensor | Polyphosphazene