Cellular uptake, genotoxicity and cytotoxicity of cobalt ferrite magnetic nanoparticles in human breast cells
Yazarlar (6)
Elif Aşik Middle East Technical University (Metu), Türkiye
Dr. Öğr. Üyesi Yeliz AKPINAR Kırşehir Ahi Evran Üniversitesi, Türkiye
N. Tülin Güray
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Mesude Işcan
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Gonca Çakmak Demircigil
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Mürvet Volkan
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Toxicology Research | ||
| Dergi ISSN | 2045-452X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 5 / 6 / 1649–1662 | DOI | 10.1039/c6tx00211k |
| Makale Linki | https://academic.oup.com/toxres/article-abstract/5/6/1649/5568578 | ||
| Özet |
| Magnetic nanoparticles (MNPs) have been increasingly used for many years as MRI agents and for gene delivery and hyperthermia therapy, although there have been conflicting results on their safety. In this study, cobalt ferrite magnetic nanoparticles (CoFe-MNPs) were prepared by the co-precipitation method and their surfaces were modified with silica by the sol–gel method. The particle and hydrodynamic sizes, morphology and crystal structure of the bare and silica-coated CoFe-MNPs were evaluated by transmission electron microscopy (TEM), dynamic light scattering (DLS), X-ray diffraction spectroscopy (XRD) and Fourier transform infrared spectroscopy (FTIR). The size of the bare CoFe-MNPs was in the range 8–20 nm and they were homogeneously coated with 3–4 nm silica shells. The bare and silica-coated CoFe-MNPs were agglomerated at physiological pH. However, the sizes of the agglomerates … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 23 |
| SCOPUS | 26 |
| Google Scholar | 35 |