A Novel Acetylcholinesterase Biosensor Core Shell Magnetic Nanoparticles Incorporating a Conjugated Polymer for the Detection of Organophosphorus Pesticides
Yazarlar (8)
Hurija Dzudzevic Cancar
Univerzitet U Sarajevu, Bosna Hersek
Univerzitet U Sarajevu, Bosna Hersek
Saniye Soylemez Middle East Technical University (Metu), Türkiye
Dr. Öğr. Üyesi Yeliz AKPINAR Kırşehir Ahi Evran Üniversitesi, Türkiye
Melis Kesik
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Seza Göker
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Gorkem Gunbas
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Murvet Volkan
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
Levent Toppare
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ACS Applied Materials and Interfaces | ||
| Dergi ISSN | 1944-8244 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2016 |
| Cilt / Sayı / Sayfa | 8 / 12 / 8058–8067 | DOI | 10.1021/acsami.5b12383 |
| Özet |
| To construct a sensing interface, in the present work, a conjugated polymer and core–shell magnetic nanoparticle containing biosensor was constructed for the pesticide analysis. The monomer 4,7-di(furan-2-yl)benzo[c][1,2,5]thiadiazole (FBThF) and core–shell magnetic nanoparticles were designed and synthesized for fabrication of the biosensing device. The magnetic nanoparticles were first treated with silica and then modified using carboxyl groups, which enabled binding of the biomolecules covalently. For the construction of the proposed sensor a two-step procedure was performed. First, the poly(FBThF) was electrochemically generated on the electrode surface. Then, carboxyl group modified magnetic nanoparticles (f-MNPs) and acetylcholinesterase (AChE), the model enzyme, were co-immobilized on the polymer-coated surface. Thereby, a robust and novel surface, conjugated polymer bearing magnetic … |
| Anahtar Kelimeler |
| acetylcholinesterase | conjugated polymer | magnetic nanoparticles | organophosphorus pesticides | pesticide biosensor |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 153 |
| Scopus | 136 |
| Web of Science | 115 |