A Novel Acetylcholinesterase Biosensor Core Shell Magnetic Nanoparticles Incorporating a Conjugated Polymer for the Detection of Organophosphorus Pesticides
Yazarlar (8)
Hurıja Dzudzevıc Cancar Univerzitet U Sarajevu
Saniye Söylemez Ordu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Yeliz AKPINAR Kırşehir Ahi Evran Üniversitesi, Türkiye
Melis Kesik Middle East Technical University (Metu)
Seza Göker Orta Doğu Teknik Üniversitesi, Türkiye
Emrullah Görkem Günbaş Orta Doğu Teknik Üniversitesi, Türkiye
Mürvet Volkan
Orta Doğu Teknik Üniversitesi, Türkiye
Orta Doğu Teknik Üniversitesi, Türkiye
Levent Kamil Toppare
Orta Doğu Teknik Üniversitesi, Türkiye
Orta Doğu Teknik Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ACS Applied Materials & Interfaces | ||
| Dergi ISSN | 1944-8244 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2016 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 8 / 12 / 8058–8067 | DOI | 10.1021/acsami.5b12383 |
| Özet |
| To construct a sensing interface, in the present work, a conjugated polymer and core–shell magnetic nanoparticle containing biosensor was constructed for the pesticide analysis. The monomer 4,7-di(furan-2-yl)benzo[c][1,2,5]thiadiazole (FBThF) and core–shell magnetic nanoparticles were designed and synthesized for fabrication of the biosensing device. The magnetic nanoparticles were first treated with silica and then modified using carboxyl groups, which enabled binding of the biomolecules covalently. For the construction of the proposed sensor a two-step procedure was performed. First, the poly(FBThF) was electrochemically generated on the electrode surface. Then, carboxyl group modified magnetic nanoparticles (f-MNPs) and acetylcholinesterase (AChE), the model enzyme, were co-immobilized on the polymer-coated surface. Thereby, a robust and novel surface, conjugated polymer bearing magnetic … |
| Anahtar Kelimeler |
| acetylcholinesterase | conjugated polymer | magnetic nanoparticles | organophosphorus pesticides | pesticide biosensor |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 153 |
| Scopus | 22 |
| Web of Science | 115 |