| Yazarlar |
Şardan Melis
|
|
Serdar Sezer
|
Prof. Dr. Aslıhan GÜNEL
Ahi Evran Üniversitesi, Türkiye |
|
Mahinur Akkaya
Orta Doğu Teknik Üniversitesi, Türkiye |
|
Cihangir Tanyeli
Orta Doğu Teknik Üniversitesi, Türkiye |
| Özet |
| An efficient synthesis of racemic and both enantiomeric forms of heteroaryl substituted γ- and δ-lactone derivatives derived from allyl and homoallyl alcohol backbones has been accomplished via ring closing metathesis reaction. 2-Heteroaryl substituted allyl and homoallyl alcohols have been efficiently resolved through enzymatic method with high ee (97-99%) and known stereochemistry. Antimicrobial and antioxidant activities of target lactones were evaluated. © 2012 Published by Elsevier Ltd. |
| Anahtar Kelimeler |
| Asymmetric synthesis | Enzymatic resolution | Optically active lactones |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS |
| Dergi ISSN | 0960-894X |
| Dergi Tarandığı Indeksler | SSCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2011 |
