| Yazarlar (3) |
Arif Baran
Sakarya Üniversitesi, Türkiye |
Prof. Dr. Aslıhan GÜNEL
Sinop Üniversitesi, Türkiye |
|
Metin Balcı
İstanbul Aydın Üniversitesi, Türkiye |
| Özet |
| (Chemical Equation Presented) For the construction of the bicyclo[2.2.2]octane skeleton, 2,2-dimethyl-3a,7a-dihydro-1,3-benzodioxole was reacted with vinylene carbonate to give two isomeric cycloadditon products having the bicyclo[2.2.2]octane skeleton. Hydrolysis of the ketal ring and the opening of the carbonate functionality, followed by hydroxylation of the remaining double bond resulted in the formation of a symmetrical hexol. Epoxidation of the double bond in the cycloaddition products and the subsequent ring-opening reactions produce two additional hexol derivatives. One of the synthesized molecules exhibited enzymespecific inhibition against α-glycosidase. © 2008 American Chemical Society. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | JOURNAL OF ORGANIC CHEMISTRY |
| Dergi ISSN | 0022-3263 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SSCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2008 |
| Cilt No | 73 |
| Sayı | 12 |
| Sayfalar | 4370 / 4375 |
| Doi Numarası | 10.1021/jo800553u |
| Atıf Sayıları | |
| WoS | 21 |
| SCOPUS | 19 |
| Google Scholar | 30 |
