A versatile study of novel A3B-type unsymmetric zinc(II) phthalocyanines containing thiazolidin-4-one: Their, carbonic anhydrase I, II isoenzymes, and xanthine oxidase inhibitors evaluation
Yazarlar (4)
Emel Karakılıç
Sakarya Üniversitesi, Türkiye
Prof. Dr. Zuhal ALIM Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Aslıhan GÜNEL Kırşehir Ahi Evran Üniversitesi, Türkiye
Arif Baran Sakarya Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Molecular Structure (Q3)
Dergi ISSN 0022-2860 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 06-2022
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 1257 / 1 / 132630–0 DOI 10.1016/j.molstruc.2022.132630
Makale Linki http://dx.doi.org/10.1016/j.molstruc.2022.132630
Özet
In this study, four novel phthalocyanine complexes containing zinc metal were synthesized. After preparing the starting compounds (2-(4-hydroxyphenyl)-3-phenylthiazolidin-4-one 1 and 2-(4-(2-hydroxyethoxy)phenyl)-3-phenylthiazolidin-4-one 3 by the conventional method, they were reacted with 4-nitrophthalonitrile separately using K2CO3 in DMF. Compounds 2 and 4, are well-documented compounds for obtaining phthalocyanines. Subsequently, synthesized phthalonitrile compounds 2 and 4 were reacted with Zn(II) salt at high temperature in the presence of DBU to convert them into targeted symmetrical (2a, 4a) and unsymmetrical (2b, 4b) phthalocyanines under suitable conditions. Their photochemical, photophysical, and electrochemical features were then examined. These metallophthalocyanines indicated good solubility in some organic solvents, such as DMSO, DMF, THF, DCM, and CHCl3. Furthermore …
Anahtar Kelimeler
Carbonic anhydrase i | II | Symmetrical phthalocyanines | Thiazolidin-4-one | Unsymmetrical phthalocyanines | Voltammetry | Xanthine oxidase