In vitro anti-leishmanial activities and structure-activity relationship analysis of new antimony(III) complexes
Yazarlar (3)
Doç. Dr. Turgay TUNÇ Kırşehir Ahi Evran Üniversitesi, Türkiye
Hatice Ertabaklar Aydın Adnan Menderes Üniversitesi, Türkiye
Nurcan Karacan
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Indian Journal of Chemical Section A | ||
| Dergi ISSN | 0376-4710 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2020 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 59 / 11 / 1609–1617 | DOI | 10.56042/ijca.v59i11.27269 |
| Makale Linki | http://op.niscair.res.in/index.php/IJCA/article/view/27269/465478273 | ||
| Özet |
| New fourteen antimony (III) complexes of general formula [SbL n Cl 3](where n= 1 or 2, L= 2-aminopyridine, 5-methyl-2-aminopyridine, 2-aminopyrimidine, 4, 6-dimethoxy-2-aminopyrimidine, 2-benzyl-2-thiopseudeourea, 2-guanidinobenzimidazole, 2-amino-5-thiol-4, 6-dimethoxypyrimidine, 2-amino-5-(1H-tetrazol-5-ylthio)-4, 6-dimethoxypyrimidine, N-2-pyrimidine, 2-piperidinecarboxamide, N-2-pyrimidine, 2-pyrrolidinecarboxamide, 2-amino-5-(1H-tetrazol-5-iltiyo)-4, 6-dimethoxypyrimidine-2-pyrrolidinecarboxamide and N-2-pyrimidine, 5-chloro-2-thiophenecarboxamide, N-2-benzothiazol-2-pyrrolidinecarboxaamide, N, N-(1, 2-phenyl) dipyrrolidine-2-carboxamide) have been synthesized and their anti-leishmanial activity have been assessed in vitro against Leishmania tropica promastigotes. The best complex, Sb (2-guanidinobenzimidazole) Cl 3 is demostrated 3.16% growth inhibition at a concentration of 31.25 μg/mL. In general, antimony (III) complexes containing pyrimidine ligands has showed higher anti-leishmani... |
| Anahtar Kelimeler |
| Antimony(III) complexes | Anti-leishmanial activity | Structure-activity relationship |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 3 |