| Yazarlar |
Doç. Dr. Turgay TUNÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Prof. Dr. Nadir DEMİREL
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Mahmut Emir
|
Prof. Dr. Aslıhan GÜNEL
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Mehmet Çolak
Dicle Üniversitesi, Türkiye |
|
Nurcan Karacan
Gazi Üniversitesi, Türkiye |
| Özet |
| Three new copper(II) complexes (1-3) with general formula [Cu(HL)CH3COO] of N-salicyl-beta-amino alcohol Schiff bases containing, (S)-(+)-phenyl glycinol. (1S, 2R)-2-amino-1, 2-diphenylethanol and 1, 1, 3-triphenyl-(R)-(+)-2-amino propanol, were synthesized. Their structures were characterized by FTIR, LCMS, magnetic moment, molar conductance and elemental analysis data. DFT calculations proposed distorted square planar geometries for the complexes. The calculated IR spectra are in good agreement with the experimental IR spectra, confirming the proposed structures. Their interactions with calf thymus DNA were investigated and their binding constants K-b were found. Gel electrophoresis reveals that all complexes display significant nuclease activity against supercoiled pentry/d-topo plasmid DNA. |
| Anahtar Kelimeler |
| Copper (II) complexes | DFT calculations | DNA binding | DNA cleavage | Schiff base complexes |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | JOURNAL OF THE MEXICAN CHEMICAL SOCIETY |
| Dergi ISSN | 1870-249X |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2018 |
| Cilt No | 62 |
| Sayı | 3 |
| Sayfalar | 51 / 66 |
| Doi Numarası | 10.29356/jmcs.v62i3.424 |
| Makale Linki | https://www.jmcs.org.mx/index.php/jmcs/article/view/424 |
| Atıf Sayıları | |
| WoS | 2 |
| SCOPUS | 3 |
| Google Scholar | 3 |
