Synthesis Structural Characterization and Biological Evaluation of Novel Substituted 1 3 Thiazole Derivatives Containing Schiff Bases [III. Ulusal Organik Kimya Kongresinde sözlü sunulmuş ve özeti yayınlanmıştır]
Yazarlar (5)
Hakan Tahtacı Karabük Üniversitesi, Türkiye
Prof. Dr. Tuncay KARAKURT Kırşehir Ahi Evran Üniversitesi, Türkiye
Abdurrahman Onaran Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Heterocyclic Chemistry
Dergi ISSN 0022-152X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 01-2017
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 54 / 1 / 183–193 DOI 10.1002/jhet.2565
Makale Linki http://doi.wiley.com/10.1002/jhet.2565
Özet
In this study, thiazole derivatives containing Schiff bases (7a, 7b, 7c, 7d, 7e, 7f, 8a, 8b, 8c, 8d, 8e, 8f, 9a, 9b, 9c, 9d, 9e, 9f) were synthesized in moderate to high yields (49–94%) using the Hantzsch reaction with thiosemicarbazone derivatives (5a, 5b, 5c) and 2‐bromo‐1‐phenylethanone derivatives (6a, 6b, 6c, 6d, 6e, 6f). The structures of synthesized compounds were elucidated by IR, 1H NMR, 13C NMR, elemental analyses, mass spectroscopy and X‐ray diffraction analysis techniques. Moreover, the synthesized compounds were tested for their in vitro antifungal activity and most of them exhibited moderate to good activity against Fusariumoxysporumf.sp. lycopersici.
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