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Synthesis, Structural Characterization, and Biological Evaluation of Novel Substituted 1,3-Thiazole Derivatives Containing Schiff Bases    
Yazarlar
Hakan Tahtacı
Karabük Üniversitesi, Türkiye
Mustafa Er
Karabük Üniversitesi, Türkiye
Doç. Dr. Tuncay KARAKURT Doç. Dr. Tuncay KARAKURT
Ahi Evran Üniversitesi, Türkiye
Abdurrahman Onaran
Gaziosmanpaşa Üniversitesi, Türkiye
Özet
In this study, thiazole derivatives containing Schiff bases (7-9 a-f) were synthesized in moderate to high yields (49-94%) using the Hantzsch reaction with thiosemicarbazone derivatives (5a-c) and 2bromo- 1-phenylethanone derivatives (6a-f). The structures of synthesized compounds were elucidated by IR, H-1 NMR, C-13 NMR, elemental analyses, mass spectroscopy and X-ray diffraction analysis techniques. Moreover, the synthesized compounds were tested for their in vitro antifungal activity and most of them exhibited moderate to good activity against Fusariumoxysporumf.sp. lycopersici.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı JOURNAL OF HETEROCYCLIC CHEMISTRY
Dergi ISSN 0022-152X
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2017
Cilt No 54
Sayı 1
Sayfalar 183 / 193
Doi Numarası 10.1002/jhet.2565
Makale Linki http://doi.wiley.com/10.1002/jhet.2565