| Yazarlar (3) |
|
Hacettepe Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Sertan AYTAÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Hacettepe Üniversitesi, Türkiye |
| Özet |
| Metal triflate catalyzed addition reaction of pyrrole to methyl 2-oxo-4-phenylbut-3-enoate and substituted derivatives generated the related novel alkylated pyrroles regioselectively at C (2) of pyrrole. Among the studied metal triflates, Cu (OTf) 2 was found to be more effective in the addition reaction. The synthesized methyl 2-oxo-4-phenyl-4-(1H-pyrrole-2-yl) butanoate esters underwent self-cyclization by heating and yielded the corresponding methyl 3-hydroxy-1-phenyl-2, 3-dihydro-1H-pyrrolizine-3-carboxylate and substituted derivatives. This reaction procedure allowed easy access to pyrrolizine structure in mild reaction conditions. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Heterocycles |
| Dergi ISSN | 0931-7597 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2008 |
| Cilt No | 39 |
| Sayı | 11 |
| Sayfalar | 2427 / 2440 |
| Doi Numarası | 10.1002/chin.200811116 |
| Makale Linki | https://doi.org/10.1002/chin.200811116 |