Yazarlar (3) |
![]() Hacettepe Üniversitesi, Türkiye |
![]() Kırşehir Ahi Evran Üniversitesi, Türkiye |
![]() Hacettepe Üniversitesi, Türkiye |
Özet |
Metal triflate catalyzed addition reaction of pyrrole to methyl 2-oxo-4-phenylbut-3-enoate and substituted derivatives generated the related novel alkylated pyrroles regioselectively at C (2) of pyrrole. Among the studied metal triflates, Cu (OTf) 2 was found to be more effective in the addition reaction. The synthesized methyl 2-oxo-4-phenyl-4-(1H-pyrrole-2-yl) butanoate esters underwent self-cyclization by heating and yielded the corresponding methyl 3-hydroxy-1-phenyl-2, 3-dihydro-1H-pyrrolizine-3-carboxylate and substituted derivatives. This reaction procedure allowed easy access to pyrrolizine structure in mild reaction conditions. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
Dergi Adı | HETEROCYCLES |
Dergi ISSN | 0385-5414 Wos Dergi Scopus Dergi |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q3 |
Makale Dili | İngilizce |
Basım Tarihi | 01-2007 |
Cilt No | 71 |
Sayı | 11 |
Sayfalar | 2427 / 2440 |
Doi Numarası | 10.1002/chin.200811116 |
Makale Linki | https://www.heterocycles.jp/newlibrary/payments/form/02463/PDF |