| Yazarlar |
Dr. Öğr. Üyesi Sertan AYTAÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| In this study, new pyridine-based imine compounds (8-10) were synthesized and docking studies of these compounds against D2 Dopamine receptor (6CM4) were performed. The structures of these compounds, which were synthesized using the microwave method, were determined by 1H-NMR, 13C-NMR and elemental analysis techniques. The binding energy values vary range from -6.79 to -7.07 kcal/mol with D2 Dopamine Receptor/PDB: 6MC4. Compound 10 (-7.07 kcal mol-1) showed better binding energy than 9 (-6.95 kcal mol-1) and 8 (-6.79 kcal/mol). |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayımlanan tam makale |
| Dergi Adı | Hittite Journal of Science and Engineering |
| Dergi ISSN | 2148--4171 |
| Dergi Tarandığı Indeksler | TR Dizin , EBSCO CEEAS, EBSCO Appl.Sci.&Tech., DOAJ |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2023 |
| Cilt No | 10 |
| Sayı | 2 |
| Sayfalar | 161 / 165 |
| Doi Numarası | 10.17350/HJSE19030000303 |
| Makale Linki | https://dergipark.org.tr/tr/download/article-file/2959556 |
| Atıf Sayıları |
