Yazarlar (5) |
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![]() Kırşehir Ahi Evran Üniversitesi, Türkiye |
![]() Orta Doğu Teknik Üniversitesi, Türkiye |
![]() Orta Doğu Teknik Üniversitesi, Türkiye |
Özet |
Antitumor activity of Gemcitabine, a nucleoside analogue, has been reported in a variety of human tumors, including breast cancer in both experimental and clinical studies. Conventional chemotherapeutic agents are unspecifically distributed all over the body where they affect both cancerous and normal cells. They cause major systemic toxicities and drug resistance, which also restricts drugs therapeutic efficacy. Recent advances in nanotechnology have explored new targeting strategies for enhancing intra-tumoral drug concentrations while limiting the systemic toxicity and side effects. Controlled release of Gemcitabine within cancer cells could be achieved by PAMAM coated magnetic nanoparticles (DcMNPs) which could be targeted to the tumor tissue. |
Anahtar Kelimeler |
Bildiri Türü | Tebliğ/Bildiri |
Bildiri Alt Türü | Poster Olarak Sergilenen Tebliğ (Uluslararası Kongre/Sempozyum) |
Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum |
Bildiri Dili | İngilizce |
Kongre Adı | 11th International Symposium on Pharmaceutical Sciences (ISOPS) |
Kongre Tarihi | 09-06-2015 / 12-06-2015 |
Basıldığı Ülke | |
Basıldığı Şehir |