Yazarlar (3) |
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Özet |
Hepatitis B virus (HBV) infection is a majority problem of public health in the world. An estimated 350-400 million people worldwide are chronically infected with HBV [1, 2]. Wang et al.[3] have reported approximately 250,000 deaths to happen each year as a consequence of hepatic failure, cirrhosis and hepatocellular carcinoma.The cytokine-mediated immunity plays a crucial role in determining of hepatitis infections overcome. The variations in cytokine production may influence the outcome of cytokinebased immunotherapy [4, 5]. Cytokine gene polymorphisms were associated with the severity of the liver disease in patients with HBV infection [6]. Interleukin (IL)-18 is a pleiotropic proinflammatory cytokine. It is a member of the IL-1 family and was first identified as interferon-gamma inducing factor [7-9]. IL-18 is synthesized as a 24-kDa proform which is activated to |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayınlanan tam makale |
Dergi Adı | Journal of Experimental and Integrative Medicine |
Dergi ISSN | 1309-4572 Scopus Dergi |
Dergi Tarandığı Indeksler | EBSCO, DOAJ, ScopeMed, Index Scholar, Akademik Dizin |
Makale Dili | İngilizce |
Basım Tarihi | 01-2014 |
Cilt No | 4 |
Sayı | 3 |
Sayfalar | 175 / |
Doi Numarası | 10.5455/jeim.150514.or.105 |
Makale Linki | http://www.scopemed.org/?mno=158328 |