Synthesis optimization and characterization of chitosan coated iron oxide nanoparticles produced for biomedical applications
Yazarlar (5)
Unsoy Gozde
Prof. Dr. Serap YALÇIN AZARKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
Khodadust Rouhollah
Gunduz Ufuk
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı JOURNAL OF NANOPARTICLE RESEARCH
Dergi ISSN 1388-0764 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 11-2012
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 14 / 11 / 964–0 DOI 10.1007/s11051-012-0964-8
Makale Linki http://link.springer.com/10.1007/s11051-012-0964-8
Özet
The chitosan-coated magnetic nanoparticles (CS MNPs) were in situ synthesized by cross-linking method. In this method; during the adsorption of cationic chitosan molecules onto the surface of anionic magnetic nanoparticles (MNPs) with electrostatic interactions, tripolyphosphate (TPP) is added for ionic cross-linking of the chitosan molecules with each other. The characterization of synthesized nanoparticles was performed by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS/ESCA), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), thermal gravimetric analysis (TGA), and vibrating sample magnetometry (VSM) analyses. The XRD and XPS analyses proved that the synthesized iron oxide was magnetite (Fe3O4). The layer of chitosan on the magnetite surface was confirmed by FTIR. TEM results demonstrated a spherical …
Anahtar Kelimeler
Iron oxide (Fe3O4) | Chitosan | Magnetic nanoparticle | Biomedicine