Significance of fascin expression in laryngeal squamous cell carcinoma
Yazarlar (6)
A Durmaz Gulhane Training & Research Hospital, Türkiye
B Kurt Gulhane Training & Research Hospital, Türkiye
S Karahatay Gulhane Training & Research Hospital, Türkiye
Mustafa Gerek Gülhane Askeri Tıp Akademisi, Türkiye
Prof. Dr. Serap YALÇIN AZARKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | JOURNAL OF LARYNGOLOGY AND OTOLOGY | ||
| Dergi ISSN | 0022-2151 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2010 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 124 / 2 / 194–198 | DOI | 10.1017/S0022215109991630 |
| Makale Linki | http://www.journals.cambridge.org/abstract_S0022215109991630 | ||
| Özet |
| ObjectiveFascin is an actin-binding protein which is expressed in the basal areas of healthy squamous epithelium. Although overexpression of fascin has been shown in many tumours, the relationship between fascin and laryngeal squamous cell carcinoma has not previously been investigated, to the best of our knowledge. This study aimed to investigate the relationship between fascin expression and tumour behaviour in 30 cases of laryngeal squamous cell carcinoma.Materials and methodsFor all lesions, a section of paraffin-embedded tissue was immunohistochemically stained for fascin. The percentage of positive, stained cells was scored from one to five (one = 0–5 per cent, two = 6–25 per cent, three = 26–50 per cent, four = 51–75 per cent and five = 76–100 per cent), and the staining intensity from one to three (one = mild, two = moderate and three = strong). A total immunohistochemical fascin expression … |
| Anahtar Kelimeler |
| Larynx Neoplasms | Squamous Cell Carcinoma | Fascin |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 32 |
| Web of Science | 19 |