Yazarlar |
Serap YALÇIN AZARKAN
Ahi Evran Üniversitesi, Türkiye |
Özlem Özlüer
|
Ufuk Gündüz
Orta Doğu Teknik Üniversitesi, Türkiye |
Özet |
Development of novel drug-delivery systems aims to specifically deliver anticancer drugs to tumor tissues and improve the efficiency of chemotherapy, while minimizing side effects of drugs on healthy tissues and organs. However, drug-delivery systems are confronted by membrane barriers and multiple drug resistance in cancer cells. In recent years, the obtained results indicate an important role of lipids, proteins and carbohydrates in apoptosis, drug transport and the process of cellular uptake of nanoparticles via endocytosis. This article discusses the hypothesis of the relationship between cell membrane structure and nanoparticles in cancer cells. |
Anahtar Kelimeler |
cancer | cell membrane structures | nanoparticles |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | ESCI dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | THERAPEUTIC DELIVERY |
Dergi ISSN | 2041-5990 |
Dergi Tarandığı Indeksler | Chemical Abstracts•EMBASE/Excerpta Medica•EMCare•Emerging Sources Citation Index (Web of Science)•MEDLINE/Index Medicus•Scopus |
Makale Dili | İngilizce |
Basım Tarihi | 11-2016 |
Cilt No | 7 |
Sayı | 11 |
Sayfalar | 773 / 781 |
Doi Numarası | 10.4155/tde-2016-0056 |
Atıf Sayıları | |
WoS | 9 |
Google Scholar | 8 |