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Nanoparticle based drug delivery in cancer the role of cell membrane structures     
Yazarlar
 Serap YALÇIN AZARKAN Serap YALÇIN AZARKAN
Ahi Evran Üniversitesi, Türkiye
Özlem Özlüer
Ufuk Gündüz
Orta Doğu Teknik Üniversitesi, Türkiye
Özet
Development of novel drug-delivery systems aims to specifically deliver anticancer drugs to tumor tissues and improve the efficiency of chemotherapy, while minimizing side effects of drugs on healthy tissues and organs. However, drug-delivery systems are confronted by membrane barriers and multiple drug resistance in cancer cells. In recent years, the obtained results indicate an important role of lipids, proteins and carbohydrates in apoptosis, drug transport and the process of cellular uptake of nanoparticles via endocytosis. This article discusses the hypothesis of the relationship between cell membrane structure and nanoparticles in cancer cells.
Anahtar Kelimeler
cancer | cell membrane structures | nanoparticles
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü ESCI dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı THERAPEUTIC DELIVERY
Dergi ISSN 2041-5990
Dergi Tarandığı Indeksler Chemical Abstracts•EMBASE/Excerpta Medica•EMCare•Emerging Sources Citation Index (Web of Science)•MEDLINE/Index Medicus•Scopus
Makale Dili İngilizce
Basım Tarihi 11-2016
Cilt No 7
Sayı 11
Sayfalar 773 / 781
Doi Numarası 10.4155/tde-2016-0056