| Yazarlar (2) |
Prof. Dr. Serap YALÇIN AZARKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Ufuk Gündüz
Orta Doğu Teknik Üniversitesi, Türkiye |
| Özet |
| Nanoparticle-based targeted drug delivery is a successful strategy to overcome the side effect of chemotherapy. Nanoparticles based drug delivery systems that have been designed to enhance delivery of therapeutics to tumors, are a novel approach. Nanoparticles have reactive surface that can be readily modified with biocompatible coatings and loaded with therapeutic agents (miRNA, siRNA, antibody, anti-cancer drug etc..). MicroRNAs (miRNAs or miRs) are short non-coding RNAs which posttranscriptionally regulate growth, differentiation, apoptosis, motility, and malignant transformation. In addition, some miRNAs have been classified as proto-oncogenes. The levels of changed miRNA expression play significant role in the initiation of many diseases, including cancer, especially tumor progression and metastasis. Further studies, miRNA conjugation to drug carrier systems is used to target to cancer cells. In this review, we focus on miRNA carrier nanoparticles, and summarize novel advances about their use in drug resistance breast cancer therapy. |
| Anahtar Kelimeler |
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Journal of Nanomedicine and nanotechnology |
| Dergi Tarandığı Indeksler | Chemical Abstracts Service (CAS)HINARIIndex CopernicusGoogle ScholarSherpa RomeoOpen J GateGenamics JournalSeekAcademic KeysJournalTOCsResearchBibleChina National Knowledge Infrastructure (CNKI)Polish Scholarly Bibliography (PBN)WTI-FrankfurtUlrich's Periodicals DirectoryElectronic Journals LibraryRefSeekHamdard UniversityEBSCO A-ZOCLC- WorldCatProquest SummonsSWB online catalogVirtual Library of Biology (vifabio)SciLit - Scientific LiteraturePublons |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2016 |
