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Exosomes as delivery tools in cancer therapy: Future perspectives   
Yazarlar
Fatma Kübra Ata
Prof. Dr. Serap YALÇIN AZARKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Özet
Exosomes, which are one of the extracellular vesicles, are considered necessary tools of intracellular communication that abundant in our body in physiological and pathological conditions with a diameter of 30-150 nm. The nanotubes, dendrimeric, metallic, nanoparticles have been used in the medical area. However, these nano-based systems are lack of standardized manufacturing methods and therefore, it has toxic effects on cells. The delivery methods of growth factors, exosomes, cells, and engineered tissues have notably advanced in the medical area. The fact that they contain bioactive molecules such as protein, lipid, RNA and DNA revealed that these structures may play an important role in the treatment of cancer. Here, we review work on the contribution exosomal mediated cancer treatment in two main topics as exogenous molecule carrier and self-use. We also emphasize the development of exosome-based systems by referring to the advantages and disadvantages of using exosomes and future perspectives in cancer therapy.
Anahtar Kelimeler
Advantages, Cancer treatment, Cancer diagnosis, Disadvantages Exosome, Nanoparticle
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü ESCI dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Nanomedicine Journal
Dergi ISSN 2322-5904
Dergi Tarandığı Indeksler E-SCI
Makale Dili Türkçe
Basım Tarihi 01-2021
Makale Linki https://en.civilica.com/l/75720/
BM Sürdürülebilir Kalkınma Amaçları
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