Exosomes as delivery tools in cancer therapy: Future perspectives
Yazarlar (2)
Fatma Kübra Ata
Kirsehir Ahi Evran University, Türkiye
Prof. Dr. Serap YALÇIN AZARKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (ESCI dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale) | ||
| Dergi Adı | NANOMEDICINE JOURNAL | ||
| Dergi ISSN | 2322-3049 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | E-SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 03-2021 |
| Cilt / Sayı / Sayfa | 8 / 3 / 156–165 | DOI | 10.22038/NMJ.2021.56215.1572 |
| Makale Linki | https://en.civilica.com/l/75720/ | ||
| Özet |
| Exosomes, which are one of the extracellular vesicles, are considered necessary tools of intracellular communication that abundant in our body in physiological and pathological conditions with a diameter of 30-150 nm. The nanotubes, dendrimeric, metallic, nanoparticles have been used in the medical area. However, these nano-based systems are lack of standardized manufacturing methods and therefore, it has toxic effects on cells. The delivery methods of growth factors, exosomes, cells, and engineered tissues have notably advanced in the medical area. The fact that they contain bioactive molecules such as protein, lipid, RNA and DNA revealed that these structures may play an important role in the treatment of cancer. Here, we review work on the contribution exosomal mediated cancer treatment in two main topics as exogenous molecule carrier and self-use. We also emphasize the development of exosome-based systems by referring to the advantages and disadvantages of using exosomes and future perspectives in cancer therapy. |
| Anahtar Kelimeler |
| Advantages | Cancer treatment | Cancer diagnosis | Disadvantages Exosome | Nanoparticle |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |