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Determination of Antioxidant Activities of Viscum album L.: First Report on Interaction of Phenolics with Survivin Protein using in silico Analysis    
Yazarlar (8)
Safiye Elif Korcan
Türkiye
Nevin Çankaya
Uşak Üniversitesi, Türkiye
Prof. Dr. Serap YALÇIN AZARKAN Prof. Dr. Serap YALÇIN AZARKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
İbrahim Bulduk
Türkiye
Emre Can Karaaslan
Mustafa Kargıoğlu
Türkiye
Muhsin Konuk
Türkiye
Gencer Güvercin
Devamını Göster
Özet
Mistletoe, Viscum album L., (VA) known as “Ökse Otu” in Turkey, is a hemiparasitic shrub that grows especially on the trunks and crowns of broadleaf trees. This study is aimed to determination of the VA’s antioxidant compounds and evaluate their in vitro activities growing on twelve different host trees and determination of in silico approach of compounds against survivin protein. At the same time, the active ingredients determined in HPLC analysis, were performed with molecular docking and molecular dynamics analysis on survivin protein, an apoptosis inhibitor protein in cancer. Antioxidant activities of methanolic extracts of organs of VA were determined. Phytochemical properties of different organs of VA samples taken from different hosts varied as well. Total phenolic content was determined at the highest rate in fruits, followed by leaves and branches, respectively. Total flavonoid content was determined in …
Anahtar Kelimeler
Antioxidant Activity | Flavonoid | Mistletoe | Phenolic | Viscum album L
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Wiley
Dergi ISSN 2365-6549 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili Türkçe
Basım Tarihi 03-2023
Cilt No 8
Sayı 12
Doi Numarası 10.1002/slct.202300130
Makale Linki http://dx.doi.org/10.1002/slct.202300130