Aspergillus fumigatus mycovirus causes mild hypervirulent effect on pathogenicity when tested on Galleria mellonella
Yazarlar (2)
Doç. Dr. Selin ÖZKAN KOTİLOĞLU Imperial College London, İngiltere
Robert Ha Coutts
Imperial College London, İngiltere
Imperial College London, İngiltere
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | FUNGAL GENETICS AND BIOLOGY (Q2) | ||
| Dergi ISSN | 1087-1845 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2015 |
| Cilt / Sayı / Sayfa | 76 / 0 / 20–26 | DOI | 10.1016/j.fgb.2015.01.003 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S1087184515000067 | ||
| Özet |
| Mycoviruses are a specific group of viruses that naturally infect and replicate in fungi. The importance of mycoviruses was revealed after their effects were identified not only in economically important fungi but also in the human pathogenic fungus Aspergillus fumigatus. The latter was shown recently to harbor at least three different types of mycoviruses including a chrysovirus, a partitivirus and an as yet uncharacterized virus. Assessment of virulence in the presence and absence of mycoviruses in A. fumigatus is pivotal to understanding its pathogenicity. Here, we have investigated, for the first time, the effects of mycoviruses on the pathogenicity of A. fumigatus as assessed using larvae of the greater wax moth Galleria mellonella. In order to observe the effects of mycoviruses on pathogenicity, G. mellonella were injected with virus-free and virus-infected isolates of A. fumigatus and post-infection survival times were … |
| Anahtar Kelimeler |
| Aspergillus fumigatus | dsRNAs | Mycoviruses | Galleria mellonella | Virulence | Pathogenicity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 63 |
| Google Scholar | 91 |