| Yazarlar (2) |
Doç. Dr. Özlem KARA
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Asuman Kilitci
Düzce Üniversitesi, Türkiye |
| Özet |
| Abstract Background/Aim: The use of doxorubicin is limited due to its toxic effects on normal cells. A substance containing antioxidant properties, such as taraxacum officinale, would be useful in preventing doxorubicin toxicity. This study aimed to evaluate the effect of taraxacum officinale on doxorubicin-induced damage in the rat liver. Methods: Forty Wistar albino rats were allocated into four groups. In group 1 (control group), no treatment was given. In group 2 (Taraxacum officinale, group T), 100 mg/kg Taraxacum officinale was administered via the gavage route for 10 days. In group 3 (doxorubicin, group D), a single intraperitoneal dose of 40 mg/kg doxorubicin was given. In group 4 (doxorubicin+ Taraxacum officinale, group D+ T), a single intraperitoneal dose of 40 mg/kg doxorubicin was administered on the eighth day, and 100 mg/kg Taraxacum officinale was administered for 10 days. Blood malondialdehyde … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | journal surgery and medicine |
| Dergi ISSN | 2602-2079 |
| Dergi Tarandığı Indeksler | ESCI, pubmed |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2023 |
| Cilt No | 7 |
| Sayı | 6 |
| Sayfalar | 379 / 382 |
| Doi Numarası | 10.28982/josam.7464 |
| Makale Linki | https://jsurgmed.com/article/view/7464 |
| Atıf Sayıları | |
| Google Scholar | 1 |
