img
Physico-Chemical Changes of Composite Whey Protein Hydrogels in Simulated Gastric Fluid Conditions    
Yazarlar
Barış Özel
Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Özlem AYDIN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Leonid Grunin
Halil Mecit Öztop
Orta Doğu Teknik Üniversitesi, Türkiye
Özet
Polysaccharide blended whey protein isolate (WPI) hydrogels were developed for the delivery of black carrot (Daucus carota) concentrate as bioactive agent in simulated gastric fluid (SGF). Pectin (PC), gum tragacanth (GT), and xanthan gum (XG) were blended as additional polymers to modulate the release characteristics of the WPI hydrogels. Experiments showed that sole whey protein (C), XG, and GT blended hydrogels possessed restricted release profiles 67%, 61%, and 67%, respectively, whereas PC samples attained higher release rates (83%) (p < 0.05). Interactions between polymers and aqueous medium were analyzed by nuclear magnetic resonance relaxometry. C (82 ms) and GT (84 ms) hydrogels attained higher T-2 values than PC (74 ms) and XG (73 ms) samples in SGF. Hardness of only XG hydrogels increased from 1.9 to 4.1 N after gastric treatment. Physicochemical changes within hydrogels during release were also investigated, and hydrogels were proved to be appropriate for desired delivery purposes.
Anahtar Kelimeler
hydrogel, whey, black carrot release, SGF, NMR, FTIR
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Journal of Agricultural and Food Chemistry
Dergi ISSN 0021-8561
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 08-2018
Cilt No 66
Sayı 36
Sayfalar 9542 / 9555
Doi Numarası 10.1021/acs.jafc.8b02829
Makale Linki http://pubs.acs.org/doi/10.1021/acs.jafc.8b02829