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Highly selective intermolecular one-pot three component 1,3-dipolar cycloaddition reaction of aldehydes, with phosphonates and proline    
Yazarlar (3)
Dr. Öğr. Üyesi Nuriye Tuna SUBAŞI Dr. Öğr. Üyesi Nuriye Tuna SUBAŞI
Ahi Evran Üniversitesi, Türkiye
Hatice Yalçınkaya
Ayhan S Demir
Devamını Göster
Özet
The use of L-proline to act as an organocatalyst in the aldol reaction of acylphosphonates and non enolizable aldehydes failed; however, it reacted with the aldehydes to afford azomethine ylides after decarboxylation that in turn underwent 1,3-dipolar cycloaddition with the acylphosphonates to form a bicyclic hexahydropyrrolo[1,2-c]oxazol-1-ylphosphonates in good yield. No azomethine ylide formation was observed on the reaction of acylphosphonates with proline.
Anahtar Kelimeler
Acylphosphonate | Azomethine ylide | Dipolar cycloaddition | Proline
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Tetrahedron
Dergi ISSN 0040-4020 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 07-2017
Cilt No 73
Sayı 30
Sayfalar 4329 / 4334
Doi Numarası 10.1016/j.tet.2017.05.091
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0040402017306002