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Highly selective intermolecular one-pot three component 1,3-dipolar cycloaddition reaction of aldehydes, with phosphonates and proline    
Yazarlar (3)
Dr. Öğr. Üyesi Nuriye Tuna SUBAŞI Dr. Öğr. Üyesi Nuriye Tuna SUBAŞI
Kırşehir Ahi Evran Üniversitesi, Türkiye
Hatice Yalçınkaya
Middle East Technical University (Metu), Türkiye
Ayhan S Demir
Devamını Göster
Özet
The use of L-proline to act as an organocatalyst in the aldol reaction of acylphosphonates and non enolizable aldehydes failed; however, it reacted with the aldehydes to afford azomethine ylides after decarboxylation that in turn underwent 1,3-dipolar cycloaddition with the acylphosphonates to form a bicyclic hexahydropyrrolo[1,2-c]oxazol-1-ylphosphonates in good yield. No azomethine ylide formation was observed on the reaction of acylphosphonates with proline.
Anahtar Kelimeler
Acylphosphonate | Azomethine ylide | Dipolar cycloaddition | Proline
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Tetrahedron
Dergi ISSN 0040-4020 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 07-2017
Cilt No 73
Sayı 30
Sayfalar 4329 / 4334
Doi Numarası 10.1016/j.tet.2017.05.091
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0040402017306002