Intermolecular one-pot cyclization of formyl-pyrroles of amino acid esters with norephedrine: stereoselective routes to new tricyclic pyrrole–pyrazine–oxazole fused structures
Yazarlar (3)
Ayhan S Demir Middle East Technical University (Metu)
Dr. Öğr. Üyesi Nuriye Tuna SUBAŞI Ahi Evran Üniversitesi, Türkiye
Ertan Şahin Atatürk Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Tetrahedron: Asymmetry
Dergi ISSN 0957-4166 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 09-2006
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 17 / 18 / 2625–2631 DOI 10.1016/j.tetASY.2006.09.020
Makale Linki http://dx.doi.org/10.1016/j.tetasy.2006.09.020
Özet
The treatment of esters of amino acids with dimethoxytetrahydrofuran furnished pyrrole derivatives of amino acid esters. The Wilsmeier–Haack formylation followed by the reaction of the formylated pyrroles with norephedrine afforded a selective formation of the tricyclic pyrrole–pyrazine–oxazole fused structures in one step via the formation of an o...
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