Pre opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre operative Serum Calcium and Alkaline Phosphatase Levels
  
Yazarlar (10)
Makale Türü Açık Erişim Özgün Makale (Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
Dergi Adı Medicine Science
Dergi ISSN 2147-0634
Dergi Tarandığı Indeksler Index Scholar- ScopeMed- Google Scholar- Akademik Dizin- Free Journals Act- Türkiye Atıf Dizini- TUBİTAK ULAKBİM DergiPark Akademik
Makale Dili İngilizce Basım Tarihi 01-2015
Cilt / Sayı / Sayfa 4 / 3 / 2401–2413 DOI 10.5455/medscience.2015.04.8257
Makale Linki http://www.scopemed.org/?mno=172492
Özet
The aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014. Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study. The mean pre-operative serum calcium and intact PTH (iPTH) levels were 11.98±1.23 mg/dl and 386.52±374.96 pg/ml, respectively. Serum pre-operative calcium levels were found to be significantly higher in patients who had nephrolithiasis than those who did not, whereas pre-operative serum phosphate levels were lower. Pre-operative iPTH levels were found to be correlated with pre-operative calcium, alkaline phosphatase and MDPA but not with preoperative serum phosphate. Also, pre-operative calcium levels were found to be significantly correlated with MDPA.Conclusion: Presence of nephrolithiasis is associated with higher preoperative calcium and lower phosphate levels. Pre-operative iPTH and calcium levels were also found to be significantly correlated with MDPA; this suggests that serum iPTH and calcium levels can be useful in predicting MDPA
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