| Yazarlar |
Ayla Balaban Gündüzalp
Gazi Üniversitesi, Türkiye |
Prof. Dr. Neslihan ÖZBEK
Ahi Evran Üniversitesi, Türkiye |
|
Nurcan Karacan
Gazi Üniversitesi, Türkiye |
| Özet |
| Carboxamide complexes having general formula as [ML]Cl2.nH 2O (where M = Cu(II), Zn(II); n = 0, 1/2) were synthesized using heterocyclic carboxamide ligands: 1,4-bis[3-(2-thiophenecarboxamido)propyl] piperazine (L1) and 1,4-bis[3-(2-furancarboxamido) propyl] piperazine (L2). Their structures were characterized with elemental analysis, molar conductivity, magnetic susceptibility, and spectral methods ( 1H-NMR, 13C-NMR, FT-IR, LC-MS). TGA and DTA curves were also performed. The structure-Activity relationship for the ligands was investigated using PM3 semi-empirical method. The antibacterial activities of the carboxamides and their complexes were investigated against bacteria; Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 11230, Bacillus magaterium RSKK 5117, B. cereus RSKK 863, Salmonella enteritidis ATCC 13076, B. subtilis RSKK 244 using microdilution method. © Springer Science+Business Media, LLC 2011. |
| Anahtar Kelimeler |
| 2-Furancarbonyl chloride | 2-Thiophenecarbonyl chloride | 4-Bis(3-Aminopropyl)piperazine | Antibacterial activity | Carboxamides | Microdilution method |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | MEDICINAL CHEMISTRY RESEARCH |
| Dergi ISSN | 1054-2523 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 11-2012 |
| Cilt No | 21 |
| Sayı | 11 |
| Sayfalar | 3435 / 3444 |
| Doi Numarası | 10.1007/s00044-011-9878-8 |
| Makale Linki | http://link.springer.com/10.1007/s00044-011-9878-8 |
| Atıf Sayıları | |
| WoS | 26 |
| SCOPUS | 28 |
| Google Scholar | 32 |
