Synthesis characterization and antimicrobial activity of copper II complexes with N N propanediyl bis benzenesulfonamide and N N ethanediyl bis 2 methylbenzenesulfonamide
Yazarlar (4)
Karatekin University, Türkiye
Prof. Dr. Neslihan ÖZBEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Ondokuz Mayis Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Medicinal Chemistry Research | ||
| Dergi ISSN | 1054-2523 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2013 |
| Cilt / Sayı / Sayfa | 22 / 5 / 2051–2060 | DOI | 10.1007/s00044-012-0171-2 |
| Makale Linki | http://link.springer.com/10.1007/s00044-012-0171-2 | ||
| Özet |
| Copper(II) complexes of new aryldisulfonamides (L 1 = N,N′-bis[(2-methylphenyl)sulfonyl]ethylenediamine) and L 2 = N,N′-propanediyl-bis-benzenesulfonamide with 1,10-phenanthroline have been synthesized and characterized by using elemental analyses, FT-IR, LCMS, conductivity, and magnetic susceptibility techniques. The structures of [Cu(phen) 2 ]L 1 (1) and [CuL 2 (phen) 2 ] (2) compounds have been determined. Complex (1) has also been characterized by single crystal X-ray diffraction. The complex (1) crystallizes in the triclinic system, space group P1, with cell constants a = 12.9353(8) Å, b = 13.8543(9) Å, c = 14.4513(10) Å, α = 103.593(5), β = 113.713(5), γ = 106.104(5), and Z = 1. The antibacterial activities of synthesized compounds were studied against Gram-positive bacteria: Staphylococcus aureus, Bacillus subtilis, and B. cereus and Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa, and Yersinia enterocolitica by microdilution (as MICs in μg/mL) and disk diffusion (as diameter zone in mm) method. The biological activity screening showed that (1) has more activity than (2) against the tested bacteria. © 2012 Springer Science+Business Media, LLC. |
| Anahtar Kelimeler |
| Antimicrobial activity | Disk diffusion method | MICs | Sulfonamide Cu(II) complexes |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 16 |
| SCOPUS | 14 |
| Google Scholar | 17 |