Characterization antibacterial anticarbonic anhydrase II isoenzyme anticancer electrochemical and computational studies of sulfonic acid hydrazide derivative and its Cu II complex
Yazarlar (8)
Ümmühan Özdemir Gazi Üniversitesi, Türkiye
Ebru Aktan Gazi Üniversitesi, Türkiye
Firdevs Ilbiz Gazi Üniversitesi, Türkiye
Ayla B. Gündüzalp Gazi Üniversitesi, Türkiye
Prof. Dr. Neslihan ÖZBEK Kırşehir Ahi Evran Üniversitesi, Türkiye
Musa Sari Gazi Üniversitesi, Türkiye
Ömer Çelik Dicle Üniversitesi, Türkiye
Sinan Saydam Firat Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Inorganica Chimica Acta
Dergi ISSN 0020-1693 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 11-2014
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 423 / 0 / 194–203 DOI 10.1016/j.ica.2014.09.033
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0020169314006057
Özet
A new N′-acetyl butane sulfonic acid hydrazide, C4H9-SO2-NH-NH-COCH3 (Absh, an sulfonamide compound), and its Cu(II) complex [Cu(Absh)2(CH3COO)2], have been synthesized and characterized by elemental analysis, spectrometric methods (1H–13C NMR, FT-IR, LC–MS), thermal analysis, magnetic susceptibility and conductivity measurements. In addition, molecular structure of the ligand, Absh was determined by single crystal X-ray diffraction technique and found that the compound crystallizes in monoclinic, space group P21/c. To gain information about the structure of the ligand and its complex, we have performed computational studies using density functional theory (DFT) for optimized geometries of the compounds. Electrochemical studies showed that, the complex is electrochemically active and has one irreversible reduction and one irreversible oxidation potentials, and the half wave reduction …
Anahtar Kelimeler
Biological activities | Butane sulfonic acid hydrazide | Crystal structure | Cu(II) complex | DFT | Electrochemical studies