Synthesis characterization and anti microbial evaluation of Cu II Ni II Pt II and Pd II sulfonylhydrazone complexes 2D QSAR analysis of Ni II complexes of sulfonylhydrazone derivatives
Yazarlar (5)
Prof. Dr. Neslihan ÖZBEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Karatekin University, Türkiye
Karatekin University, Türkiye
Atatürk Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy | ||
| Dergi ISSN | 1386-1425 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2013 |
| Cilt / Sayı / Sayfa | 108 / 1 / 123–132 | DOI | 10.1016/j.saa.2013.01.005 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S1386142513000310 | ||
| Özet |
| Copper(II), nickel(II), platinum(II) and palladium(II) complexes with 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) derived from propanesulfonic acid-1-methylhydrazide (psmh) were synthesized, their structure were identified, and antimicrobial activity of the compounds was screened against three Gram-positive and three Gram-negative bacteria. The results of antimicrobial studies indicate that Pt(II) and Pd(II) complexes showed the most activity against all bacteria. The crystal structure of 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) was also investigated by X-ray analysis. A series of Ni(II) sulfonyl hydrazone complexes (1-33) was synthesized and tested in vitro against Escherichia coli and Staphylococcus aureus. Their antimicrobial activities were used in the QSAR analysis. Four-parameter QSAR models revealed that nucleophilic reaction index for Ni and O atoms, and HOMO-LUMO energy gap play key roles in the antimicrobial activity. © 2013 Elsevier B.V. All rights reserved. |
| Anahtar Kelimeler |
| 2D-QSAR | Antimicrobial activity | Ni(II) sulfonyl hydrazone derivatives | Sulfonylhydrazide | Sulfonylhydrazone | X-ray structure |
Science Direct
Synthesis characterization and anti microbial evaluation of Cu II Ni II Pt II and Pd II sulfonylhydrazone complexes 2D QSAR analysis of Ni II complexes of sulfonylhydrazone derivatives
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 38 |
| SCOPUS | 41 |
| Google Scholar | 45 |