| Yazarlar |
Prof. Dr. Neslihan ÖZBEK
Ahi Evran Üniversitesi, Türkiye |
Alyar Saliha
|
|
Nurcan Karacan
Gazi Üniversitesi, Türkiye |
| Özet |
| Methanesulfonic acid 1-methylhydrazide (msmh) and its sulfonyl hydrazone derivatives, salicylaldehyde-N-methylmethanesulfonylhydrazone (salmsmh) and 2-hydroxy-1-naphthaldehyde-N-methylmethanesulfonylhydrazone (nafmsmh) were synthesized and characterized by using FT-IR, 1H NMR, 13C NMR, LC-MS and elemental analysis. Conformation analysis of msmh based on DFT/B3LYP/6-311G(d) method was performed. 1H and 13C shielding tensors of msmh for the most stable conformer were calculated with GIAO/DFT/B3LYP/6-311++G(2d, 2p) methods in vacuo and various solvents such as DMSO, THF, acetonitrile, methanol and aqueous solution. The harmonic vibrational wavenumbers for the most stable conformer were calculated using at B3LYP/6-311G(d) level. Antimicrobial activity of the compounds was also screened against Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus RSKK 863) and Gram-negative bacteria (Escherichia coli ATCC 11230, Salmonella enterititis ATCC 40376, Pseudomonos aeruginosa ATCC 28753) by both disc diffusion and micro dilution methods. © 2009 Elsevier B.V. All rights reserved. |
| Anahtar Kelimeler |
| Antimicrobial activity | DFT | NMR spectra | Sulfonyl hydrazide | Sulfonyl hydrazone |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal of Molecular Structure |
| Dergi ISSN | 0022-2860 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2009 |
| Cilt No | 938 |
| Sayı | 1 |
| Sayfalar | 48 / 53 |
| Doi Numarası | 10.1016/j.molstruc.2009.09.002 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0022286009005663 |
| Atıf Sayıları | |
| WoS | 31 |
| SCOPUS | 29 |
| Google Scholar | 37 |
