Experimental and theoretical studies on methanesulfonic acid 1 methylhydrazide Antimicrobial activities of its sulfonyl hydrazone derivatives
Yazarlar (3)
Prof. Dr. Neslihan ÖZBEK Kırşehir Ahi Evran Üniversitesi, Türkiye
Saliha Alyar Gazi Üniversitesi, Türkiye
Nurcan Karacan Gazi Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Molecular Structure
Dergi ISSN 0022-2860 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 12-2009
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 938 / 1 / 48–53 DOI 10.1016/j.molstruc.2009.09.002
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0022286009005663
Özet
Methanesulfonic acid 1-methylhydrazide (msmh) and its sulfonyl hydrazone derivatives, salicylaldehyde-N-methylmethanesulfonylhydrazone (salmsmh) and 2-hydroxy-1-naphthaldehyde-N-methylmethanesulfonylhydrazone (nafmsmh) were synthesized and characterized by using FT-IR, 1H NMR, 13C NMR, LC–MS and elemental analysis. Conformation analysis of msmh based on DFT/B3LYP/6-311G(d) method was performed. 1H and 13C shielding tensors of msmh for the most stable conformer were calculated with GIAO/DFT/B3LYP/6-311++G(2d,2p) methods in vacuo and various solvents such as DMSO, THF, acetonitrile, methanol and aqueous solution. The harmonic vibrational wavenumbers for the most stable conformer were calculated using at B3LYP/6-311G(d) level. Antimicrobial activity of the compounds was also screened against Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus …
Anahtar Kelimeler
Antimicrobial activity | DFT | NMR spectra | Sulfonyl hydrazide | Sulfonyl hydrazone