Alkyl sulfonic acide hydrazides Synthesis characterization computational studies and anticancer antibacterial anticarbonic anhydrase II hCA II activities
Yazarlar (7)
Ummuhan O. Ozdemir
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Firdevs Ilbiz
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Ayla Balaban Gunduzalp Gazi Üniversitesi, Türkiye
Prof. Dr. Neslihan ÖZBEK Kırşehir Ahi Evran Üniversitesi, Türkiye
Zuhal Karagoz Genç
Adiyaman Üniversitesi, Türkiye
Adiyaman Üniversitesi, Türkiye
Fatma Hamurcu Bartin Üniversitesi, Türkiye
Suat Tekin Inönü Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure | ||
| Dergi ISSN | 0022-2860 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2015 |
| Cilt / Sayı / Sayfa | 1100 / 1 / 464–474 | DOI | 10.1016/j.molstruc.2015.07.054 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0022286015301654 | ||
| Özet |
| Methane sulfonic acide hydrazide, CH3SO2NHNH2 (1), ethane sulfonic acide hydrazide, CH3CH2SO2NHNH2 (2), propane sulfonic acide hydrazide, CH3CH2CH2SO2NHNH2 (3) and butane sulfonic acide hydrazide, CH3CH2CH2CH2SO2NHNH2 (4) have been synthesized as homologous series and characterized by using elemental analysis, spectrophotometric methods (1H–13C NMR, FT-IR, LC-MS). In order to gain insight into the structure of the compounds, we have performed computational studies by using 6–311G(d, p) functional in which B3LYP functional were implemented. The geometry of the sulfonic acide hydrazides were optimized at the DFT method with Gaussian 09 program package. A conformational analysis of compounds were performed by using NMR theoretical calculations with DFT/B3LYP/6–311++G(2d, 2p) level of theory by applying the (GIAO) approach. The anticancer activities of these … |
| Anahtar Kelimeler |
| Alkyl sulfonic acide hydrazide | Anti carbonic anhydrase II isoenzyme | Antibacterial | Anticancer | Computational studies | Sulfonamide |
Science Direct
Alkyl sulfonic acide hydrazides Synthesis characterization computational studies and anticancer antibacterial anticarbonic anhydrase II hCA II activities
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 39 |
| Scopus | 33 |
| Web of Science | 31 |