Yazarlar |
Ümmühan Özdemir Özmen
Gazi Üniversitesi, Türkiye |
Nesrin Akkaya
|
Neslihan ÖZBEK
Ahi Evran Üniversitesi, Türkiye |
Özet |
Methanesulfonicacid hydrazide (a sulfonamide compound, msh: CH 3SO2NHNH2) derivatives: salicylaldehydemethanesulfonylhydrazone (salmsh), 2- hydroxyacetophenonemethanesulfonyl hydrazone (afmsh), 2-hydroxy-3- metoxybenzaldehydemethanesulfonylhydrazone (o-vanmsh) and their Ni(II), Pd(II) and Pt (II) complexes have been synthesized. The structure of these compounds has been investigated by using elemental analyses; FT-IR, 1H- NMR, LC - MS, UV-Visible spectrometric methods; magnetic susceptibility; conductivity measurements; thermal studies. The antibacterial activities of synthesized compounds have been determined in vitro against gram positive bacteria; Staphylococcus aureus ATCC 25923, Bacillus cereus RSKK 709, and gram negative bacteria; Pseudomonos aeruginosa ATCC 27853, Escherichia coli ATCC 35268 by paper disc diffusion and microdilution broth methods. The biological activity screening showed that metal complexes have more activity than their ligands against the tested bacteria. © 2013 Elsevier B.V. All rights reserved. |
Anahtar Kelimeler |
Antibacterial activity | Aromatic methanesulfonylhydrazone | Ni(II) | Pd(II) | Pt(II) complexes | sulfonamide Sulfonamide derivatives |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | INORGANICA CHIMICA ACTA |
Dergi ISSN | 0020-1693 |
Dergi Tarandığı Indeksler | SCI |
Makale Dili | İngilizce |
Basım Tarihi | 05-2013 |
Cilt No | 400 |
Sayı | 1 |
Sayfalar | 13 / 19 |
Doi Numarası | 10.1016/j.ica.2013.01.031 |
Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0020169313000339 |