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New nickel II palladium II platinum II complexes with aromatic methanesulfonylhydrazone based ligands Synthesis spectroscopic characterization and in vitro antibacterial evaluation      
Yazarlar
Ümmühan Özdemir Özmen
Gazi Üniversitesi, Türkiye
Nesrin Akkaya
Prof. Dr. Neslihan ÖZBEK
Ahi Evran Üniversitesi, Türkiye
Özet
Methanesulfonicacid hydrazide (a sulfonamide compound, msh: CH 3SO2NHNH2) derivatives: salicylaldehydemethanesulfonylhydrazone (salmsh), 2- hydroxyacetophenonemethanesulfonyl hydrazone (afmsh), 2-hydroxy-3- metoxybenzaldehydemethanesulfonylhydrazone (o-vanmsh) and their Ni(II), Pd(II) and Pt (II) complexes have been synthesized. The structure of these compounds has been investigated by using elemental analyses; FT-IR, 1H- NMR, LC - MS, UV-Visible spectrometric methods; magnetic susceptibility; conductivity measurements; thermal studies. The antibacterial activities of synthesized compounds have been determined in vitro against gram positive bacteria; Staphylococcus aureus ATCC 25923, Bacillus cereus RSKK 709, and gram negative bacteria; Pseudomonos aeruginosa ATCC 27853, Escherichia coli ATCC 35268 by paper disc diffusion and microdilution broth methods. The biological activity screening showed that metal complexes have more activity than their ligands against the tested bacteria. © 2013 Elsevier B.V. All rights reserved.
Anahtar Kelimeler
Antibacterial activity | Aromatic methanesulfonylhydrazone | Ni(II) | Pd(II) | Pt(II) complexes | sulfonamide Sulfonamide derivatives
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Inorganica Chimica Acta
Dergi ISSN 0020-1693
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 05-2013
Cilt No 400
Sayfalar 13 / 19
Doi Numarası 10.1016/j.ica.2013.01.031
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0020169313000339