Synthesis of novel chiral Schiff base ligands and their application in asymmetric nitro aldol Henry reaction
    
Yazarlar (4)
Mehmet Çolak
Dicle Üniversitesi, Türkiye
Tarık Aral
Dicle Üniversitesi, Türkiye
Halil Hoşgören
Dicle Üniversitesi, Türkiye
Prof. Dr. Nadir DEMİREL Dicle Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Tetrahedron Asymmetry
Dergi ISSN 0957-4166 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2007
Cilt / Sayı / Sayfa 18 / 9 / 1129–1133 DOI 10.1016/j.tetasy.2007.04.025
Özet
Chiral Schiff-bases prepared from chiral amino alcohols catalyze the enantioselective Henry (nitro aldol) reaction between nitromethane and p-nitrobenzaldehyde in the presence of Cu(OTf)2 and Zn(OTf)2. Zn(OTf)2 promoted the reaction yield, while Cu(OTf)2 promoted the enantiomeric excess. The highest enantioselectivities were observed with ligand 3 (44% ee) and ligand 5 (47% ee). © 2007 Elsevier Ltd. All rights reserved.
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