Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015
Yazarlar (3)
Mustafa Güzel Hitit Üniversitesi, Türkiye
Mürşide Dilek Avşaroğlu Erkan Kırşehir Ahi Evran Üniversitesi, Türkiye
Yeşim Soyer Orta Doğu Teknik Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale) | ||
| Dergi Adı | Food and Health | ||
| Dergi ISSN | 2602-2834 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2020 |
| Cilt / Sayı / Sayfa | 6 / 3 / 160–169 | DOI | – |
| Makale Linki | https://scientificwebjournals.com/JFHS/Vol6/issue3/FH20017.pdf | ||
| Özet |
| Antimicrobial resistance of pathogenic microorganisms is an emerging public health concern. Intensive use of antibiotics in food animals might increase antimicrobial resistance in foodbornepathogens. Colistin is a last resort antibiotic for treatment of multidrug resistant (MDR) Gramnegative pathogens. The recent antimicrobial resistance studies revealed a mobile antimicrobialresistance gene (mcr) that provides resistance to colistin. Furthermore, the gene has been found indifferent genera. Therefore, the aim of this study was to determine colistin resistance of Escherichia coli isolates (N=48) isolated in between 2011 and 2015 from food samples in Turkey. In addition, 5 mcr genes and their variants were screened by performing PCR on resistant isolates. 4 E.coli isolates were found resistant to colistin above the epidemiological cut-off value (Minimuminhibitory concentration (MIC) > 2mg/L). None of the resistant isolates had the mcr genes. Furtherstudies with human and food isolates should be conducted to figure out which gene or genes areresponsible for colistin resistance. |
| Anahtar Kelimeler |