| Yazarlar |
Mustafa Kemal Başaralı
|
|
İbrahim Kaplan
Dicle Üniversitesi, Türkiye |
Prof. Dr. Muttalip ÇİÇEK
Dicle Üniversitesi, Türkiye |
|
Fatih Çakır
|
| Özet |
| The aim of our study is to evaluate the relationship between trace elements, as zinc (Zn) and copper (Cu), and acute phase reactant ceruloplasmin (CP) levels during fascioliasis hepatic infection. 45 patients with fascioliasis and 38 healthy controls were enrolled in the study. Fascioliasis was diagnosed with ELISA IgG, stool examination and radiologic imaging. Number of females and males were determined as 34/11 and 30/8 in patient and control groups respectively. Mean age was 38.1±11.7 and 35.8±16.9 years in patient and control groups, respectively. Blood samples were collected to determine plasma Zn, Cu, and CP levels. As a result of the study serum Cu (from 1.4 to 1.8) and CP (from 26.7 to 33.4) levels were rised in while Zn (from 1.1 to 1.9) level was decreased in patient group. We determinated significant correlation (r: 0.781) of fasciola titers with ceruloplasmine that increased by acute phase in the patients with fascioliasis. In conclusion, an high correlation between CP and Cu levels in patients suffering from fascioliasis can be noted. On the other hand, low Zn levels, especially in endemic areas of disease, suggested that Zn can be given in addition to medical treatment, or as a dietary supplement. This situation may lead the way in terms of increasing the efficiency of treatment of fascioliasis. |
| Anahtar Kelimeler |
| Ceruloplasmin | Copper | Fascioliasis | Zinc |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Acta Medica Mediterranea |
| Dergi ISSN | 0393-6384 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2013 |
| Cilt No | 29 |
| Sayı | 177 |
| Sayfalar | 177 / 181 |
