| Yazarlar |
Yavuz Tokgöz
Türkiye |
|
Müsemma Karabel
Dicle Üniversitesi, Türkiye |
|
Gökhan Baysoy
İstanbul Medipol Üniversitesi, Türkiye |
|
Cemil Göya
Yüzüncü Yıl Üniversitesi, Türkiye |
Prof. Dr. Muttalip ÇİÇEK
Ahi Evran Üniversitesi, Türkiye |
|
Ayfer Gözü Pirinççioğlu
Dicle Üniversitesi, Türkiye |
|
Ünal Uluca
|
|
Velat Şen
Dicle Üniversitesi, Türkiye |
| Özet |
| BACKGROUND: The data on childhood fascioliasis are limited. We aimed to heighten physicians' awareness of Fasciola Hepatica by presenting 14 cases in this paper. METHODS: The medical records of pediatric patients treated for F. Hepatica infection within the last 2 years were reviewed. ELISA method with a cut-off level of 10 was used as the serological test, in which an absorbance level of >11 DU/mL was considered positive. RESULTS: Ten (71.4%) patients were female. Complaints at presentation were abdominal pain (N.=14; 100%) and loss of appetite (N.=12; 85.7%). Twelve (85.7%) patients were from rural areas. All patients had an elevated eosinophil count (mean: 3885.6/mm3, minimum: 566/mm3, maximum: 18687/mm3). Six patients had a leucocyte count >10.000 cells/mm3 and 8 (57%) patients had an ESR>20 mm/h. Gamma-glutamyt transferase (GGT) was normal in all but 1 patient presenting with cholangitis. In hepatobiliary ultrasonography (USG) the most common finding was a heterogeneous solid lesion found in 11 patients. advanced imaging methods revealed multiple cystic lesions in 10 patients and magnetic resonance imaging (MRI) showed hypo-hyperintense hepatic parenchymal changes in 9 patients. The patients were started on Triclabendazole 10 mg/kg/dose. Clinical, laboratory, and radiological findings of the patients were improved after the therapy. CONCLUSIONS: Fascioliasis should be suspected in children from endemic regions presenting with abdominal pain, weight loss, and fever, which are accompanied by eosinophilia, elevation in transaminases, and cystic/solid lesions in liver, particularly in bile ducts or parenchyma. Triclabendazole is very effective for treatment of this disease. |
| Anahtar Kelimeler |
| Child | Fasciola hepatica | Parasitic diseases |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE |
| Dergi ISSN | 1827-1812 |
| Dergi Tarandığı Indeksler | ESCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2017 |
| Cilt No | 176 |
| Sayı | 11 |
| Sayfalar | 603 / 609 |
| Doi Numarası | 10.23736/S0393-3660.17.03430-1 |
| Makale Linki | https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2017N11A0603 |
| Atıf Sayıları |
