Fasciola hepatica infestation in Turkish children
Yazarlar (8)
Yavuz Tokgöz
Diyarbakýr Children Hospital, Türkiye
Müsemma Karabel
Dicle Üniversitesi, Türkiye
Gökhan Baysoy
Dicle Üniversitesi, Türkiye
Cemil Göya
Dicle Üniversitesi, Türkiye
Prof. Dr. Muttalip ÇİÇEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Ayfer G. Pirinççiodlu
Dicle Üniversitesi, Türkiye
Ünal Uluca
Dicle Üniversitesi, Türkiye
Velat Şen
Dicle Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Gazzetta Medica Italiana Archivio Per Le Scienze Mediche | ||
| Dergi ISSN | 0393-3660 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2017 |
| Cilt / Sayı / Sayfa | 176 / 11 / 603–609 | DOI | 10.23736/S0393-3660.17.03430-1 |
| Makale Linki | https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2017N11A0603 | ||
| Özet |
| BACKGROUND: The data on childhood fascioliasis are limited. We aimed to heighten physicians' awareness of Fasciola Hepatica by presenting 14 cases in this paper. METHODS: The medical records of pediatric patients treated for F. Hepatica infection within the last 2 years were reviewed. ELISA method with a cut-off level of 10 was used as the serological test, in which an absorbance level of >11 DU/mL was considered positive. RESULTS: Ten (71.4%) patients were female. Complaints at presentation were abdominal pain (N.=14; 100%) and loss of appetite (N.=12; 85.7%). Twelve (85.7%) patients were from rural areas. All patients had an elevated eosinophil count (mean: 3885.6/mm3, minimum: 566/mm3, maximum: 18687/mm3). Six patients had a leucocyte count >10.000 cells/mm3 and 8 (57%) patients had an ESR>20 mm/h. Gamma-glutamyt transferase (GGT) was normal in all but 1 patient presenting with cholangitis. In hepatobiliary ultrasonography (USG) the most common finding was a heterogeneous solid lesion found in 11 patients. advanced imaging methods revealed multiple cystic lesions in 10 patients and magnetic resonance imaging (MRI) showed hypo-hyperintense hepatic parenchymal changes in 9 patients. The patients were started on Triclabendazole 10 mg/kg/dose. Clinical, laboratory, and radiological findings of the patients were improved after the therapy. CONCLUSIONS: Fascioliasis should be suspected in children from endemic regions presenting with abdominal pain, weight loss, and fever, which are accompanied by eosinophilia, elevation in transaminases, and cystic/solid lesions in liver, particularly in bile ducts or parenchyma. Triclabendazole is very effective for treatment of this disease. |
| Anahtar Kelimeler |
| Child | Fasciola hepatica | Parasitic diseases |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |