| Yazarlar |
Cem Çelik
Cumhuriyet Üniversitesi, Türkiye |
Prof. Dr. Mustafa Gökhan GÖZEL
Cumhuriyet Üniversitesi, Türkiye |
|
Mustafa Zahir Bakıcı
Cumhuriyet Üniversitesi, Türkiye |
|
Serdar Berk
Cumhuriyet Üniversitesi, Türkiye |
|
Sefa Levent Özşahin
Cumhuriyet Üniversitesi, Türkiye |
|
Esra Gültürk
Cumhuriyet Üniversitesi, Türkiye |
| Özet |
| Background/aim: The aim of this study is to assess the Xpert MTB/RIF assay for diagnosis of the Mycobacterium tuberculosis complexin clinical samples and to compare the results by reference to the diagnostic method, Bactec MGIT 960. Materials and methods: A total of 7407 samples were included from patients not primarily suggesting pulmonary or extrapulmonarytuberculosis (TB), collected from patients required to be screened for TB and excluding TB diagnoses since it was a differential diagnosis.Also included were a total of 411 samples from patients primarily suggesting pulmonary or extrapulmonary TB.Results: In the first group, 152 of 7407 samples yielded positive results with the Bactec MGIT 960, 131 (1.77%) were found positivewith Löwenstein Jensen medium, and 295 (3.99%) were found positive with Ziehl Neelsen staining. In the second group, 24 (5.8%), 17(4.1%), and 28 (6.8%) of 411 samples were found positive. Xpert MTB/RIF [27 (6.6%) of 411 samples] detected 3 additional samples aspositive, and these 3 cases were clinically compatible with TB. Conclusion: The Xpert MTB/RIF assay shows superior performance for the diagnosis of TB. Its usefulness in culture-negative patientsand the best method for integrating this diagnostic method into current tuberculosis diagnostic algorithms both need further study. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | TURKISH JOURNAL OF MEDICAL SCIENCES |
| Dergi ISSN | 1300-0144 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2015 |
| Cilt No | 45 |
| Sayfalar | 1329 / 1334 |
| Doi Numarası | 10.3906/sag-1407-56 |
| Makale Linki | http://online.journals.tubitak.gov.tr/openDoiPdf.htm?mKodu=sag-1407-56 |
| Atıf Sayıları | |
| TRDizin | 2 |
