| Yazarlar |
Prof. Dr. Mustafa KARA
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Ethem Serdar Yalvaç
Yozgat Bozok Üniversitesi, Türkiye |
|
Taylan Onat
Türkiye |
|
Emre Başer
Türkiye |
|
Melike Demir Çaltekin
Türkiye |
|
Demet Aydoğan Kırmızı
Türkiye |
|
Müjgan Ercan Karadağ
Türkiye |
| Özet |
| Objective: The aim was to evaluate the possible effects of anti-angiogenic factors including soluble endoglin (sEng), placental growth factor (Pgf), and soluble fms-like tyrosine kinase 1 (sFlt-1) in both normotensive pregnant patients and preeclampsia (PE) patients. Material and Methods: The study was carried out at the Departments of Gynecology and Obstetrics and Biochemistry of Yozgat Bozok University Training and Research Hospital. Eighteen women with PE who were pregnant for at least 20 weeks comprised the study group. The control group consisted of 33 pregnant women with no complications and with similar demographic features. In the study, laboratory parameters, demographic characteristics, sEng, sFlt-1, and Pgf levels, delivery type, APGAR scores of the infants, and birthweight were determined and a comparison was made between the groups. Results: It was found that the sEng level was significantly lower in the PE group compared to the control group (p<0.05). In addition, the Pgf, birthweight, and 1st and 5th-minute APGAR scores were significantly lower in the PE group compared to the control group (p<0.05). Conclusion: The decrease in Pgf may have an effect on the pathogenesis of PE and can be utilized for the determination of PE. (J Turk Ger Gynecol Assoc 2021; 22: 212-6) |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal of the Turkish German Gynecological Association |
| Dergi ISSN | 1309-0380 |
| Dergi Tarandığı Indeksler | esci, pubmed |
| Makale Dili | İngilizce |
| Basım Tarihi | 10-2021 |
| Cilt No | 22 |
| Sayı | 3 |
| Sayfalar | 212 / 216 |
| Makale Linki | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420743/ |
