Paraoxonase anti oxidant response and oxidative stress in children with chronic renal failure
Yazarlar (7)
Aydin Ece
Dicle Üniversitesi, Türkiye
Dicle Üniversitesi, Türkiye
Yildiz Atamer Dicle Üniversitesi, Türkiye
Fuat Gürkan
Dicle Üniversitesi, Türkiye
Dicle Üniversitesi, Türkiye
Mehmet Davutoǧlu
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Meki Bilici
State Hospital, Türkiye
State Hospital, Türkiye
Murat Tutanç Dicle Üniversitesi, Türkiye
Prof. Dr. Ali GÜNEŞ Dicle Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Pediatric Nephrology | ||
| Dergi ISSN | 0931-041X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SSCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2006 |
| Cilt / Sayı / Sayfa | 21 / 2 / 239–245 | DOI | 10.1007/s00467-005-2079-2 |
| Özet |
| Increased oxidative stress is believed to contribute to an increased risk of cardiovascular disease in uraemia. In children with chronic renal failure (CRF), an anti-oxidant enzyme, paraoxonase (PON), that inhibits oxidation of LDL-cholesterol, has not been previously investigated. In this study we aimed to investigate PON activity, total anti-oxidant response (TAR), total peroxide (TPX), oxidative stress index (OSI) and some pro-oxidant cytokines in 29 children with CRF [mean age 10.2±3.5 years; 19 pre-dialysis, ten on continuous ambulatory peritoneal dialysis (CAPD)] and in 25 control subjects. Children with CRF had lower PON and TAR and higher TPX and OSI values than did controls (P<0.05). Except for lower TAR and serum albumin levels of the CAPD subgroup (P<0.05), other parameters were similar in non-dialysis and CAPD patients (P>0.05). Patients had significant positive correlation between TAR and … |
| Anahtar Kelimeler |
| Albumin | Children | Chronic renal failure | Cytokines | Oxidative stress | Paraoxonase |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 37 |
| Scopus | 2 |