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Ydj1 but not Sis1 stabilizes Hsp70 protein under prolonged stress in vitro    
Yazarlar
Dr. Öğr. Üyesi Lütfi TUTAR
Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Yusuf Tutar
Özet
Yeast cytosol has two important co-chaperons; Ydj1 and Sis1. Genetic experiments showed that Ydj1 is not I essential for viability; however, cells lacking it grow very poorly at 30 degrees C or unable to grow at extreme temperatures. On the other hand, Sis1 is an essential protein and apparently plays a functional role at assembly or disassembly of protein complexes. Stability experiments revealed that only Ydj1-protected Hsp70 proteins can hydrolyze ATP under prolonged stress. (c) 2007 Wiley Periodicals, Inc.
Anahtar Kelimeler
stability, Hsp70, Ydj1, Sis1
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Biopolymers
Dergi ISSN 0006-3525
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 03-2008
Cilt No 89
Sayı 3
Sayfalar 171 / 174
Doi Numarası 10.1002/bip.20881
Makale Linki http://doi.wiley.com/10.1002/bip.20881
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 23
Ydj1 but not Sis1 stabilizes Hsp70 protein under prolonged stress in vitro

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