MicroRNAs and Cancer an Overview
     
Yazarlar (3)
Dr. Öğr. Üyesi Lütfi TUTAR Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Esen Tutar Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Yusuf Tutar Cumhuriyet Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Current Pharmaceutical Biotechnology
Dergi ISSN 1389-2010 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2014
Cilt / Sayı / Sayfa 15 / 5 / 430–437 DOI 10.2174/1389201015666140519095304
Makale Linki http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1389-2010&volume=15&issue=5&spage=430
Özet
MiRNAs are a family of small, endogenous, and evolutionarily conserved non-coding ribonucleic acids that have been involved in the regulation of several essential, cellular, and functional processes. MicroRNAs are known to play key roles in all types of cancer and function as oncogenes (oncomirs) or tumour-suppressors in up-regulation or down-regulation processes respectively. MiRNAs have potential power to be examined as prognostic and diagnostic biomarkers. Modulating miRNAs, based on two major approaches (miRNA mimics and miRNA antagonists), is used for clinical development of therapeutic miRNAs. This review emphasizes the latest discovery in the field of miRNA research involved in cancer, biomarkers, and therapeutics.
Anahtar Kelimeler
Biomarkers, cancer, microRNAs, therapeutics
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 73
SCOPUS 76
Google Scholar 95
MicroRNAs and Cancer an Overview

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