Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
Yazarlar (6)
Prof. Dr. Yusuf Tutar Cumhuriyet Üniversitesi, Türkiye
Aykut Özgür Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Esen Tutar
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Dr. Öğr. Üyesi Lütfi TUTAR Kırşehir Ahi Evran Üniversitesi, Türkiye
Alessandra Pulliero Università Degli Studi Di Genova, İtalya
Alberto Izzotti Università Degli Studi Di Genova, İtalya
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Biomedicine and Pharmacotherapy (Q2) | ||
| Dergi ISSN | 0753-3322 Dergi Bilgileri (2016) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2016 |
| Cilt / Sayı / Sayfa | 83 / 1 / 1182–1190 | DOI | 10.1016/j.biopha.2016.08.043 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0753332216306916 | ||
| UAK Araştırma Alanları |
Moleküler Biyoloji ve Genetik
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| Özet |
| Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic agents. microRNAs (miRNAs) and pseudogenes are critical biomarkers in lung cancer and alteration of their expression levels has been identified in each step of lung cancer tumorigenesis. miRNAs and pseudogenes are crucial gene regulators in normal cells as well as in lung cancer cells, and they have both oncogenic and tumor-suppressive roles in lung cancer tumorigenesis. In this study, we have determined the relationship between lung cancer related oncogenes and miRNAs along with pseudogenes in lung cancer, and the results indicate their potential as biological markers for diagnostic and therapeutic purposes. |
| Anahtar Kelimeler |
| Biomarker | Lung cancer | miRNA | miRNA therapeutics | Pseudogene |
Science Direct
Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 29 |
| Scopus | 30 |
| Google Scholar | 29 |