| Yazarlar |
Doç. Dr. Burç Esra ŞAHİN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Asuman Çelikbilek
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Yusuf Koçak
Türkiye |
Dr. Öğr. Üyesi Aydan KÖYSÜREN
Ahi Evran Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Lokman HİZMALİ
Türkiye |
| Özet |
| Objectives: Data are limited regarding the relationship of neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and platelet/ lymphocyte ratio (PLR) with neurological symptoms (NS) in COVID-19 patients. This study is the first to assess the utility of the NLR, MLR, and PLR for predicting COVID-19 severity in infected patients with NS. Materials and Methods: Consecutive 192 PCR-positive COVID-19 patients with NS were included in this cross-sectional and prospective study. The patients were classified into the non-severe and severe groups. We analyzed routinely complete blood count in these groups in terms of COVID-19 disease severity. Results: Advanced age, a higher body mass index, and comorbidities were significantly more common in the severe group (P < 0.001). Among the NS, anosmia (P = 0.001) and memory loss (P = 0.041) were significantly more common in the non-severe group. In the severe group, the lymphocytes and monocyte counts and the hemoglobin level were significantly lower, while the neutrophil count, NLR, and PLR were significantly higher (all P < 0.001). In the multivariate model, advanced age and a higher neutrophil count were independently associated with severe disease (both P < 0.001) but the NLR and PLR were not (both P > 0.05). Conclusion: We found positive associations of COVID-19 severity with the NLR and PLR in infected patients with NS. Further research is required to shed more on the role of involvement in disease and outcomes. |
| Anahtar Kelimeler |
| COVID-19 | Monocyte to lymphocyte ratio | Neurological symptoms | Neutrophil to lymphocyte ratio | Platelet to lymphocyte ratio |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE |
| Dergi ISSN | 0976-3147 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2023 |
| Cilt No | 14 |
| Sayı | 2 |
| Sayfalar | 224 / 229 |
| Doi Numarası | 10.25259/JNRP_6_2022 |
| Makale Linki | http://dx.doi.org/10.25259/jnrp_6_2022 |
| Atıf Sayıları | |
| WoS | 1 |
