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Intravitreal bevacizumab treatment for refractory diabetic macular edema      
Yazarlar (2)
Prof. Dr. Kemal ÖRNEK Prof. Dr. Kemal ÖRNEK
Kırıkkale Üniversitesi, Türkiye
Nurgül Örnek
Kırıkkale Üniversitesi, Türkiye
Devamını Göster
Özet
Aims: The aim of this study was to report the short-term clinical and angiographic outcomes after an intravitreal injection of bevacizumab in eyes with refractory diabetic macular edema.
Methods: Patients who had been treated with both grid-laser photocoagulation and intravitreal trimacinolone acetonide injections for diabetic macular edema received intravitreal bevacizumab (0.125 mg/0.05 mL). Snellen visual acuity testing and fluorescien angiography were performed before and 1 month after the injection for each patient.
Results: Seventeen (17) eyes of 16 patients were included in the study. All patients completed 6 weeks of follow-up. Visual acuity improved in 12 eyes (70%) and remained the same in 5 eyes (30%). Eight (8) eyes (47%) revealed a marked improvement of macular edema, 6 eyes (35%) revealed mild improvement, and 3 eyes (18%) had no change. None of the patients developed local or systemic adverse events.
Conclusions: Intravitreal injection of bevacizumab may be effective in the treatment of refractory diabetic edema unresponsive to laser photocoagulation and in intravitreal triamcinolone injection.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
Dergi ISSN 1080-7683 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 08-2008
Cilt No 24
Sayı 4
Sayfalar 403 / 407
Doi Numarası 10.1089/jop.2007.0128