| Yazarlar (6) |
Mehmet Erhan Yumuşak
Kırıkkale Üniversitesi, Türkiye |
|
Aydın Çifci
Kırıkkale Üniversitesi, Türkiye |
|
Selim Yalçın
Kırıkkale Üniversitesi, Türkiye |
|
Cemile Dayangan Sayan
Kırıkkale Üniversitesi, Türkiye |
|
Nevin Hande Dikel
Kırıkkale Üniversitesi, Türkiye |
Prof. Dr. Kemal ÖRNEK
Kırıkkale Üniversitesi, Türkiye |
| Özet |
| Background: The aim of this study was to investigate the potential significance of the central macular thickness (foveal thickness-FT) and choroidal thickness (CT) in the eyes of patients with iron-deficiency anemia, the most common form of the anemia, via enhanced-depth imaging optical coherence tomography (EDI-OCT). We also investigated whether such changes might serve as an early indicator of underlying hematological disease. Methods: This prospective clinical study compared 96 female patients with iron-deficiency anemia and 60 healthy female control subjects. The macular and choroidal thicknesses in the temporal and nasal subfoveal areas were measured using enhanced-depth imaging optical coherence tomography (EDI-OCT) at 500 and 1500 microns and in five different regions (FCT, T-1500, T-500, N-500, and N-1500). Results: The mean ages of the patients and healthy controls were 34.08 +/- 10.39 years and 32.29 +/- 8.28 years, respectively (P = 0.232). There were no significant changes in macular thickness between the groups (225.58 +/- 19.76 vs. 222.45 +/- 13.51, P = 0.2). The choroidal thickness was significantly reduced in the patient group relative to the controls at all measured points (foveal choroidal thickness, P = 0.042; nasal-500 microns, P = 0.033; temporal-500 microns, P = 0.033; and temporal-1500 microns, P = 0.019). At some points, the choroidal thickness findings correlated with the hemoglobin values (temporal-500 microns, r = -0.287, P = 0.001; nasal-500 microns, r = -0.287, P = 0.005; nasal-1500 microns, r = -0.245, P = 0.016; and temporal-1500 microns, r = -0.280, P = 0.06). Conclusions: Patients with iron-deficiency anemia had a significantly reduced choroidal thickness. |
| Anahtar Kelimeler |
| Choroidal thickness | Iron-deficiency anemia | Enhanced-depth imaging optical coherence tomography |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | BMC OPHTHALMOLOGY |
| Dergi ISSN | 1471-2415 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2015 |
| Cilt No | 15 |
| Sayı | 1 |
| Doi Numarası | 10.1186/s12886-015-0163-3 |
| Atıf Sayıları | |
| WoS | 15 |
| SCOPUS | 16 |
| Google Scholar | 25 |
