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Corneal endothelial changes following a single session of selective laser trabeculoplasty for pseudoexfoliative glaucoma.      
Yazarlar (2)
Nurgül Örnek
Kırıkkale Üniversitesi, Türkiye
Prof. Dr. Kemal ÖRNEK Prof. Dr. Kemal ÖRNEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
PurposeTo evaluate corneal endothelial cell parameters after a single session of selective laser trabeculoplasty (SLT) in pseudoexfoliative glaucoma (PEG) patients.MethodsCorneal endothelial cell parameters of 18 PEG patients were compared with 18 healthy subjects following SLT treatment. All patients underwent SLT treatment to 180 degrees of inferior trabecular meshwork. Corneal measurements were performed using specular microscopy (Noncon Robo SP8000, Konan Medical, Hyogo, Japan). Endothelial cell density (ECD), hexagonal cell ratio (HEX), coefficient of variation (CV) of the corneal endothelial cell layer and central corneal thickness of the patients were measured at each visit.ResultsThere was a statistically significant decrease in ECD (p=0.004) and a statistically significant increase in CV (p=0.041) at superior cornea 1week after SLT. They returned to pre-SLT values at 1month. One hour post-SLT HEX of inferior cornea was statistically significantly reduced (p=0.01). At central cornea, there was a significant increase in HEX after 1week (p=0.001). Post-SLT IOP showed a significant positive correlation with CV and significant negative correlation with HEX at superior and inferior cornea. There was no correlation between total laser energy used and endothelial cell parameters.ConclusionEffect of a single session ofSLT on corneal endothelium of PEG patients appears to be transient, and superior cornea was more affected than central and inferior cornea. All parameters returned to pre-SLT values at 1month after treatment.
Anahtar Kelimeler
Selective laser trabeculoplasty | Pseudoexfoliative glaucoma | Corneal endothelium | Central corneal thickness | Intraocular pressure
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı INTERNATIONAL OPHTHALMOLOGY
Dergi ISSN 0165-5701 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 12-2018
Cilt No 38
Sayı 6
Sayfalar 2327 / 2333
Doi Numarası 10.1007/s10792-017-0730-0